Jama cardiology

In this issue of JAMA Cardiology, Lindner and colleagues 4 report on 39 autopsy cases of patients with COVID-19 in whom pneumonia was the clinical cause of death in 35 of 39 (89.7%). While histopathologic evaluation did not meet criteria seen in acute myocarditis, ...

This analysis of data from the 2016 Global Burden of Disease Study examines the national and province-level mortality, prevalence, and disability-adjusted life-years associated with cardiovascular disease in China from 1990 to 2016.Key Points. Question Is level of high-density lipoprotein cholesterol (HDL-C) associated with an increased fracture risk in healthy older adults?. Findings In this cohort study of 16 262 community-dwelling healthy participants 70 years and older, 1659 participants experienced at least 1 fracture over a median follow-up of 4 years. In the fully adjusted model, each 1 …Key Points. Question What are the trends in characteristics and outcomes of adult heart transplant after implementation of the new heart allocation policy on October 18, 2018?. Findings In this cohort study of 15 631 patients, with the heart allocation policy change, higher-risk recipients are now undergoing transplant, with higher rates of bridging with … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Importance Primary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on risk stratification. Genome-wide polygenic risk scores (PRSs) are proposed to improve ASCVD risk estimation. Objective To determine whether genome-wide PRSs for coronary artery disease (CAD) and acute ischemic stroke improve ASCVD risk estimation with traditional clinical risk …

Our acceptance rate of 7% for original science manuscripts is on par with the other major journals in our field. After only 3 years of publishing, JAMA Cardiology’s impact factor was 11.9 in 2019 (which is reported for 2018). As anticipated, the continuous flow of manuscripts has increased the workload of our very busy editors, but we relish ...Importance One in 5 US adults older than 60 years takes fish oil supplements often for heart health despite multiple randomized clinical trials showing no data for cardiovascular benefit for supplement-range doses. Statements on the supplement labels may influence consumer beliefs about health benefits. Objectives To evaluate health claims made on the labels of fish oil …In the Short and Optimal Duration of Dual Antiplatelet Therapy After Everolimus-Eluting Cobalt-Chromium Stent-2 (STOPDAPT-2) trial, 1161 patients with acute coronary syndrome (ACS) were enrolled and randomized at 75 centers in Japan from December 2015 to December 2017, while in the STOPDAPT-2 ACS trial, 3008 patients with ACS were …Hindricks G , Potpara T , Dagres N , et al; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed …JAMA Cardiology Key Points Question What is the efficacy of evolocumab in patients with a low-density lipoprotein cholesterol level of 70 mg/dL or greater (or non–high-density lipoprotein cholesterol level of 100 mg/dL or greater) and recent (past 12 months) myocardial infarction (MI) treated with maximally tolerated high-intensity statin?Key Points. Question Are accelerometer-measured physical activity (PA) and sedentary behavior associated with incident heart failure in older women?. Findings In this cohort study of 5951 women aged 63 to 99 years, usual daily light PA, moderate to vigorous PA, and steps per day were inversely associated, and total sedentary time positively …A, Percentage of patients who achieved low-density lipoprotein cholesterol (LDL-C) levels less than 70 mg/dL and less than 55 mg/dL (to convert to millimoles per liter, multiply by 0.0259) at baseline and 2 years of follow-up in the Getting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD) registry.

Objective: To conduct a meta-analysis of all large trials assessing the associations of omega-3 fatty acid supplements with the risk of fatal and nonfatal …JAMA Cardiology. Full Text. Leaving the broken system the way it is, that’s not a solution. 1. Barack Obama. It must be recognized that our current health care delivery system has failed to adequately treat 2 of our nation’s top cardiovascular risk factors: high blood pressure (BP) and hyperlipidemia.Importance Increasing cardiology workforce diversity will expand the talent of the applicant pool and may reduce health care disparities.. Objective To assess US cardiology physician workforce demographics by sex and race/ethnicity in the context of the US population and the available pipelines of trainees.. Design, Setting, and Participants This cross-sectional study used data …JAMA Cardiology. Key Points. Question Is COVID-19 vaccination linked to the occurrence of myocarditis? Findings In this study of 7 patients with acute myocarditis, 4 occurred within 5 days of COVID-19 vaccination between February 1 and April 30, 2021. All 4 ...ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of ...JAMA Cardiology. Full Text. Once new science rolls over, if you’re not part of the steamroller, you become part of the road. Adaptation of a quote by Stewart Brand. Hypertrophic cardiomyopathy (HCM) is increasingly recognized as a relatively common disorder, with a prevalence between 1 in 200 and 1 in 500, that can present with severe ...

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Key Points. Question Is the presence of coronary artery disease, as indicated by coronary artery calcium (CAC), associated with the development of clinical coronary heart disease before age 60 years?. Finding In the Coronary Artery Risk Development in Young Adults Study, black and white Americans of both sexes aged 32 to 46 years who had any CAC (Agatston …A, Overall survival of patients with DNMT3A or TET2 mutations with a VAF greater than 0.005 to 0.01; a VAF of at least 0.01 to 0.02; a VAF of at least 0.02; and non-CHIP patients reveals dose-response of clone size and clinical outcome; B, Event-free survival free of death or rehospitalization for heart failure with DNMT3A or TET2 mutations at various … The JAMA Cardiology Patient Page is a public service of JAMA Cardiology. The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA Cardiology suggests that you consult your physician ... McMurray JJ , Adamopoulos S , Anker SD , et al; ESC Committee for Practice Guidelines. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology developed in collaboration with the Heart Failure Association (HFA) of …

The 2022 American Heart Association/American College of Cardiology/Heart Failure Society of America Guideline for the Management of Heart Failure recommends the use of cardiac biomarkers, namely natriuretic peptides and cardiac troponins, for HF classification. 4 Within this framework, ambulatory patients with elevated levels of NT …Two articles published in JAMA Cardiology from 2 academic hospitals in Wuhan, China, the epicenter of the COVID-19 pandemic, 10,11 support these concepts while also providing novel insights into the incidence and consequences of myocardial injury associated with SARS-CoV-2. Coronaviruses (CoVs) are single-stranded positive-sense RNA viruses, with the capacity for rapid mutation and recombination. Coronaviruses are known to cause respiratory or intestinal infections in humans and animals. 1 Acute respiratory infections, including influenza, respiratory syncytial virus, and bacterial pneumonias, are well-recognized triggers for cardiovascular diseases (CVD), 2,3 ... Our acceptance rate of 7% for original science manuscripts is on par with the other major journals in our field. After only 3 years of publishing, JAMA Cardiology’s impact factor was 11.9 in 2019 (which is reported for 2018). As anticipated, the continuous flow of manuscripts has increased the workload of our very busy editors, but we relish ...Key Points. Question Is high-intensity interval training (HIIT) superior to moderate-intensity continuous training (MICT) for improving cardiorespiratory fitness during a 4-week hospital-based cardiac rehabilitation program and long-term with home-based training over 12 months?. Findings In this randomized clinical trial including 93 participants, …4 Associate Editor, JAMA Cardiology. 5 Duke University School of Medicine, Durham, North Carolina. 6 Deputy Editor for Statistics, JAMA Cardiology. 7 Department of Pharmacological and Biomolecular Sciences, University of …Key Points. Question Are accelerometer-measured physical activity (PA) and sedentary behavior associated with incident heart failure in older women?. Findings In this cohort study of 5951 women aged 63 to 99 years, usual daily light PA, moderate to vigorous PA, and steps per day were inversely associated, and total sedentary time positively …JAMA Cardiology. Comment & Response. To DOAC or Not to DOAC for Left Ventricular Thrombi—What Is the Dose? Arun Manmadhan, MD; Jeffrey S. Berger, MD, MS; Tania Ahuja, PharmD. JAMA Cardiology. Key Points.van Diepen S, Fordyce CB, Wegermann ZK, et al. Organizational structure, staffing, resources, and educational initiatives in cardiac intensive care units in the United States: an American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical care Cardiology Working Group cross sectional survey.Given the evidence of the effectiveness of statins in reducing atherosclerotic cardiovascular disease (ASCVD) events and mortality, the 2013 American College of Cardiology (ACC) and the American Heart Association (AHA) cholesterol treatment guidelines recommended high-intensity statins for most patients with ASCVD. 1 The recently updated 2018 cholesterol …

JAMA Cardiology JAMA Cardiol. 2022 Jul 1;7(7):662. doi: 10.1001/jamacardio.2021.4296. PMID: 35829713 DOI: …

Jul 1, 2018 · Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. 2009;301 (22):2331-2339. PubMed Google Scholar. Clarke R, Peden JF, Hopewell JC, et al; PROCARDIS Consortium. Genetic variants associated with Lp (a) lipoprotein level and coronary disease. N Engl J Med. 2009;361 (26):2518-2528. Key Points. Question How much would the highly atherogenic lipoprotein(a) have to be lowered to decrease the coronary heart disease outcomes in the same range as observed for a lowering of low-density lipoprotein cholesterol by 38.67 mg/dL?. Findings In this mendelian randomization analysis, it was estimated that lipoprotein(a) would have to …JAMA Cardiology. Key Points. Question Which factors are associated with the outcome of patients with RYR2 catecholaminergic polymorphic ventricular tachycardia during β-blocker treatment? Findings In this cohort study including 216 patients with RYR2 catecholaminergic polymorphic ventricular tachycardia, symptoms ...JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)August 1, 2017. Treatment of Cholesterol in 2017. Harlan M. Krumholz, MD, SM 1,2. Author Affiliations Article Information. 1 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine. 2 The Center for Outcomes Research and Evaluation, Yale–New Haven Health, New Haven, Connecticut.Key Points. Question What is the diagnostic and prognostic value of stress cardiovascular magnetic resonance imaging (CMR) for the evaluation of stable chest pain?. Findings In this systematic review and meta-analysis pooling 74 470 patients with stable chest pain over 381 357 person-years of follow-up, stress CMR yielded high diagnostic accuracy and …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …JAMA Cardiology. Full Text. Leaving the broken system the way it is, that’s not a solution. 1. Barack Obama. It must be recognized that our current health care delivery system has failed to adequately treat 2 of our nation’s top cardiovascular risk factors: high blood pressure (BP) and hyperlipidemia.JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality.

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JAMA Cardiology. Rare cases of cardiac inflammation following SARS-CoV-2 vaccination have been reported. 1-4 We reviewed the clinical records of vaccine recipients to identify cases of postvaccination myocarditis or pericarditis. Methods Forty hospitals in Washington, Oregon, Montana, and Los Angeles County, California, that …JAMA Cardiology. Key Points. Question Does routine ultrasonography guidance for femoral arterial access for cardiac procedures reduce bleeding or vascular complications? Findings In this randomized clinical trial that included 621 patients, ...Aug 1, 2022 · Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts): developed with ... Figure 1. Flow Diagram of Analyses. ASCVD indicates atherosclerotic cardiovascular disease; GRS, genetic risk score; Lp (a), lipoprotein (a); LDL-C, low-density lipoprotein cholesterol. To convert LDL-C to millimoles per liter, multiply by 0.0259; Lp (a) to milligrams per deciliter, divide by 2.4. Figure 2.All results were obtained through meta-analysis among 3 cohorts. Model 1 was adjusted by age and sex at the time of blood sample collection; model 2 was adjusted by age, sex, body mass index (BMI), smoking status, and physical activity at the time of blood sample collection; and model 3 was adjusted by age, sex, BMI, smoking status, … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology will focus on all aspects of cardiovascular medicine, including epidemiology and prevention, diagnostic ...JAMA Cardiology JAMA Cardiol. 2022 Jul 1;7(7):662. doi: 10.1001/jamacardio.2021.4296. PMID: 35829713 DOI: …Key Points. Question Can mendelian randomization identify associations between circulating cardiovascular disease–related proteins and hypertensive disorders of pregnancy (HDPs)?. Findings In this genetic association study including data from 21 758 participants for cardiovascular disease–related proteins, 393 238 female individuals for gestational …Using clinical registry data from 7 Mass General Brigham hospitals and affiliated practices, we isolated 2 cohorts of patients with cholesterol testing on 2 or more occasions who were 20 to 39 years old at the time of a qualifying LDL-C value between 2005 and 2018: cohort 1 included individuals with an LDL-C value of 190 mg/dL or …MeaningRestrictions on trans-fatty acid consumption are associated with a decrease in hospitalization for cardiovascular events. ImportanceTrans-fatty acids (TFAs) have deleterious cardiovascular effects. Restrictions on their use were initiated in 11 New York State (NYS) counties between 2007 and 2011.Figure 1. Flow Diagram of Analyses. ASCVD indicates atherosclerotic cardiovascular disease; GRS, genetic risk score; Lp (a), lipoprotein (a); LDL-C, low-density lipoprotein cholesterol. To convert LDL-C to millimoles per liter, multiply by 0.0259; Lp (a) to milligrams per deciliter, divide by 2.4. Figure 2. ….

Given the evidence of the effectiveness of statins in reducing atherosclerotic cardiovascular disease (ASCVD) events and mortality, the 2013 American College of Cardiology (ACC) and the American Heart Association (AHA) cholesterol treatment guidelines recommended high-intensity statins for most patients with ASCVD. 1 The recently updated 2018 cholesterol …JAMA Cardiology. Key Points. Question Can coronary artery calcium score identify individuals likely to derive net benefit from aspirin therapy for primary prevention of atherosclerotic cardiovascular disease? Findings In this cohort study, using participants from the Dallas Heart Study cohort who were free from atherosclerotic cardiovascular ...Information, Instructions for Authors, and additional resources for authors interested in submitting manuscripts to the JAMA Network journals—JAMA, JAMA Network Open, and the 11 JAMA specialty journals—are available for each journal below.Selected manuscripts submitted to JAMA that are not accepted may be referred to one of the specialty journals with the author's …Smoothed conditional mean plots visualizing the variation of incidence rates of myocardial infarction with 95% CI by different weather parameters. Unadjusted and adjusted incidence rate ratio (IRR) and 95% CI from regression analyses are presented with each graph. Results from the regression analyses are interpreted as change per increase in ... Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology should give ... JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …van Diepen S, Fordyce CB, Wegermann ZK, et al. Organizational structure, staffing, resources, and educational initiatives in cardiac intensive care units in the United States: an American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical care Cardiology Working Group cross sectional survey.van Diepen S, Fordyce CB, Wegermann ZK, et al. Organizational structure, staffing, resources, and educational initiatives in cardiac intensive care units in the United States: an American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical care Cardiology Working Group cross sectional survey.JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine … Jama cardiology, [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1]